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Desloratadine is a highly effective non-sedating, long-acting tricyclic antihistamine. It is the primary active metabolite of loratadine and is primarily used for treating allergic conditions. This product works by selectively antagonizing peripheral H1 receptors, thereby inhibiting the allergic response triggered by histamine release from mast cells and effectively relieving associated symptoms.
It is indicated for adults and adolescents aged 12 years and older to relieve symptoms of allergic rhinitis (including seasonal and perennial allergies), such as sneezing, runny nose, nasal itching, nasal congestion, as well as itchy eyes, burning sensation, and tearing.
| Product Name | Desloratadine |
| Appearance | White Powder |
| CAS Number | 100643-71-8 |
| Molecular Formula | C19H19ClN2 |
| Molecular Weight | 310.825 |
Desloratadine is a potent and selective peripheral histamine H1-receptor antagonist. Its primary mechanism involves competitively blocking histamine from binding to H1-receptors, preventing inflammatory events. A distinguishing feature is its non-sedating profile due to minimal blood-brain barrier penetration.
A1: Desloratadine is primarily used to relieve symptoms of allergic rhinitis, such as sneezing, runny nose, and itchy eyes, as well as chronic idiopathic urticaria.
A2: Desloratadine is a non-sedating antihistamine. It minimally crosses the blood-brain barrier, making it significantly less likely to cause drowsiness compared to traditional antihistamines.
A3: Our Desloratadine powder maintains a pharmaceutical grade purity level of over 99%, verified by HPLC testing.
A4: It should be stored in a cool, dry place away from direct sunlight. The shelf life is typically 2 years when stored correctly.
A5: The product is manufactured under GMP, ISO 9001 standards and complies with USP and BP specifications.
A6: Because it is a long-acting antihistamine, it is usually taken once daily at a fixed time for optimal results.
