Pharmaceutical CAS 100643-71-8 Desloratadine Powder Desloratadine

Still deciding? Get samples of $ !
Request Sample

Product Description

Basic Information
Model NO.
XMHT Desloratadine
Certification
GMP, HSE, ISO 9001, USP, BP
Purity
>99%
State
Powder
Appearance
White Powder
CAS No.
100643-71-8
Assay
99%
Shelf Life
2 Years
Product Description

Desloratadine is the primary active metabolite of loratadine, belonging to the third generation of tricyclic histamine H1-receptor antagonists. It works in a highly selective and non-sedating manner by potently blocking peripheral H1 receptors, thereby inhibiting histamine-induced capillary dilation and increased permeability.

This medication is known for its rapid onset and 24-hour long duration of action, making it a commonly prescribed anti-allergy drug in clinical practice. It effectively alleviates symptoms associated with allergic rhinitis and chronic idiopathic urticaria.

Technical Specifications
Product NameDesloratadine
AppearanceWhite or off white powder
CAS No.100643-71-8
Molecular FormulaC19H19ClN2
Molecular Weight310.825
Melting Point150-151 C
Application & Function
Desloratadine is a potent peripheral H1-receptor inverse agonist that stabilizes the receptor in its inactive conformation. Its molecular structure features a rigid tricyclic ring system with a substitution that limits central nervous system penetration, achieving non-sedating efficacy. The drug demonstrates additional anti-allergic properties including inhibition of inflammatory mediator release from mast cells and suppression of intercellular adhesion molecule expression on epithelial cells.
Product Display
Frequently Asked Questions
What is Desloratadine used for?
It is primarily used to treat symptoms of allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives) by blocking histamine receptors.
Is Desloratadine a sedating antihistamine?
No, it is a third-generation non-sedating antihistamine that has limited penetration into the central nervous system.
How long does the effect of Desloratadine last?
The drug provides a long duration of action, typically providing relief for up to 24 hours with a single dose.
What is the purity of your Desloratadine powder?
The assay purity of our Desloratadine powder is ≥99%, meeting pharmaceutical grade standards.
What are the storage conditions for this product?
It should be stored in a cool, dry place away from direct sunlight. The typical shelf life is 2 years when stored properly.
What certifications does the product have?
The product is manufactured according to GMP, ISO 9001 standards and complies with USP/BP specifications.

Related Products