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Desloratadine is the primary active metabolite of loratadine, belonging to the third generation of tricyclic histamine H1-receptor antagonists. It works in a highly selective and non-sedating manner by potently blocking peripheral H1 receptors, thereby inhibiting histamine-induced capillary dilation and increased permeability.
This medication is known for its rapid onset and 24-hour long duration of action, making it a commonly prescribed anti-allergy drug in clinical practice. It effectively alleviates symptoms associated with allergic rhinitis and chronic idiopathic urticaria.
| Product Name | Desloratadine |
| Appearance | White or off white powder |
| CAS No. | 100643-71-8 |
| Molecular Formula | C19H19ClN2 |
| Molecular Weight | 310.825 |
| Melting Point | 150-151 C |




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